anti- RAB11FIP2 antibody

Host

Rabbit

Uniprot ID

Q7L804

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate(PtdInsP3) and phosphatidic acid(PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment(ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.

Immunogen

RAB11 family interacting protein 2(class I)

Synonyms

KIAA0941

Observed MW

58 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IF

Recommended dilution

WB: 1:500-1:2000; IF: 1:20-1:200

Gene ID

22841

Research Area

Signal Transduction