anti- PYCR2 antibody

Host

Rabbit

Uniprot ID

Q96C36

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH(PubMed:2722838, PubMed:6894153). Involved in cellular response to oxidative stress(PubMed:25865492).

Immunogen

pyrroline-5-carboxylate reductase family, member 2

Synonyms

P5C reductase 2, P5CR 2, P5CR2, PYCR2

Observed MW

34 kDa

Reactivity

Human

Tested Application

ELISA, WB, IF

Recommended dilution

WB: 1:500-1:1000; IF: 1:20-1:200

Gene ID

29920

Research Area

Metabolism