anti- PTPN23 antibody

Host

Rabbit

Uniprot ID

Q9H3S7

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies(MVBs) via its interaction with the ESCRT-I complex(endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.

Immunogen

protein tyrosine phosphatase, non-receptor type 23

Synonyms

KIAA1471

Observed MW

179 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IP

Recommended dilution

WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:100-1:400; IF: 1:50-1:500

Gene ID

25930

Research Area

Signal Transduction, Metabolism