anti- PTGER3 antibody

Host

Rabbit

Uniprot ID

P43115

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Receptor for prostaglandin E2(PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems(By similarity).

Immunogen

prostaglandin E receptor 3(subtype EP3)

Synonyms

EP3, EP3 I, EP3 II, EP3 III, EP3 IV, EP3e, PGE receptor EP3 subtype, PGE2 R, PGE2 receptor EP3 subtype, Prostanoid EP3 receptor, PTGER3

Observed MW

48 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, IHC, WB

Recommended dilution

WB: 1:200-1:2000; IHC: 1:20-1:200

Gene ID

5733

Research Area

Signal Transduction