anti- PTCH1 antibody

Host

Rabbit

Uniprot ID

Q13635

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Acts as a receptor for sonic hedgehog(SHH), indian hedgehog(IHH) and desert hedgehog(DHH). Associates with the smoothened protein(SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.

Immunogen

patched homolog 1

Synonyms

HPE7, NBCCS, Patched, patched homolog 1, Patched1, Protein patched homolog 1, PTC, PTC1, PTCH, PTCH1, PTCH11

Observed MW

161 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:500-1:1000; IHC: 1:50-1:200

Gene ID

5727

Research Area

Neuroscience, Cell Division and Proliferation