anti- PRELID1 antibody

Host

Rabbit

Uniprot ID

Q9Y255

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin(CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid(PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs.

Immunogen

PRELI domain containing 1

Synonyms

CGI 106, PRELI, PRELI domain containing 1, PRELID1, PX19, Px19 like protein, SBBI12

Observed MW

25 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, IHC

Recommended dilution

IHC: 1:20-1:200

Gene ID

27166

Research Area

Developmental biology