anti- PPP2R2B antibody

Host

Rabbit

Uniprot ID

Q00005

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity(By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance(By similarity).

Immunogen

protein phosphatase 2(formerly 2A), regulatory subunit B, beta isoform

Synonyms

PP2A subunit B isoform beta, PP2A subunit B isoform R2 beta, PP2AB BETA, PP2APR55 BETA, PPP2R2B, PR2AB BETA, PR2AB55 BETA, PR2APR55 BETA, PR52B, PR55 BETA, SCA12

Observed MW

52 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IF, IP

Recommended dilution

WB: 1:500-1:1000; IP: 1:500-1:1000; IF: 1:10-1:100

Gene ID

5521

Research Area

Neuroscience, Signal Transduction, Metabolism