anti- PPP2R1B antibody

Host

Rabbit

Uniprot ID

P30154

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background

This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.

Immunogen

protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform

Synonyms

Observed MW

65 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, IHC, WB

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Gene ID

5519

Research Area

Signal Transduction, Metabolism