anti- PPARGC1B antibody

Host

Rabbit

Uniprot ID

Q86YN6

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1(NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.

Immunogen

peroxisome proliferator-activated receptor gamma, coactivator 1 beta

Synonyms

PERC, PGC1, PGC1B, PPARGC1

Observed MW

100-110 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, IP, WB

Recommended dilution

WB: 1:500-1:2000; IP: 1:200-1:1000

Gene ID

133522

Research Area

Metabolism