anti- PON2 antibody

Host

Rabbit

Uniprot ID

Q15165

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background

This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Immunogen

paraoxonase 2

Synonyms

Observed MW

39 kDa

Reactivity

Human, Rat

Tested Application

ELISA, IHC, WB

Recommended dilution

WB: 1:200 - 1:2000; IHC: 1:50 - 1:200

Gene ID

5445

Research Area

Cardiovascular, Metabolism