anti- POLG2 antibody

Host

Rabbit

Uniprot ID

Q9UHN1

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background

This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

Immunogen

polymerase (DNA directed), gamma 2, accessory subunit

Synonyms

MTPOLB

Observed MW

55 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, IHC, WB, IF

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Gene ID

11232

Research Area

Metabolism