anti- POFUT2 antibody

Host

Rabbit

Uniprot ID

Q9Y2G5

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin(TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition(EMT), maintaining the correct patterning of mesoderm and localization of the definite endoderm(By similarity). Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13.

Immunogen

protein O-fucosyltransferase 2

Synonyms

C21orf80, FUT13, KIAA0958

Observed MW

49 kDa,50 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB

Recommended dilution

WB: 1:500-1:2000

Gene ID

23275

Research Area

Metabolism