anti- Podocalyxin antibody

Host

Rabbit

Uniprot ID

O00592

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Podocalyxin, also known as podocalyxin-like protein 1(PODXL or PCLP1), is a transmembrane glycoprotein belonging to the CD34 family of sialomucins. Podocalyxin was originally identified as the major sialoprotein on podocytes of the kidney glomerulus, but was later found to be expressed on vascular endothelial cells and early hematopoietic progenitors. It Involved in the regulation of both adhesion and cell morphology. In addition, podocalyxin is highly expressed in embryonic stem cells and aberrant expression of podocalyxin has been implicated in a wide range of cancers.

Immunogen

podocalyxin

Synonyms

GCTM-2 antigen,Gp200,Podocalyxin-like protein 1,PC,PCLP-1,PODXL,PCLP, PCLP1

Observed MW

59 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IHC, FC

Recommended dilution

WB: 1:500-1:1000; IHC: 1:20-1:200

Gene ID

Research Area

Stem Cells, Cardiovascular