ABCbiolab
SKU:ABCF06349
anti- PKD2L1 antibody
anti- PKD2L1 antibody
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Host
Rabbit
Uniprot ID
Q9P0L9
Form
liquid
Purification
Immunogen affinity purified
Purity
>= 95%
as determined by SDS-PAGEClonality
polyclonal
Clone ID
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Pore-forming subunit of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD1L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect.
Immunogen
polycystic kidney disease 2-like 1
Synonyms
PKD2L, PKDL, TRPP3
Observed MW
92 kDa
Reactivity
Human, Mouse, Rat
Tested Application
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Gene ID
9033
Research Area
Signal Transduction, Developmental biology
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