anti- PI4K2A antibody

Host

Rabbit

Uniprot ID

Q9BTU6

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Membrane-bound phosphatidylinositol-4 kinase(PI4-kinase) that catalyzes the phosphorylation of phosphatidylinositol(PI) to phosphatidylinositol 4-phosphate(PI4P), a lipid that plays important roles in endocytosis, Golgi function, protein sorting and membrane trafficking and is required for prolonged survival of neurons. Besides, phosphorylation of phosphatidylinositol(PI) to phosphatidylinositol 4-phosphate(PI4P) is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate(PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate(InsP3).

Immunogen

phosphatidylinositol 4-kinase type 2 alpha

Synonyms

Observed MW

48-52 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB

Recommended dilution

WB: 1:500-1:2000

Gene ID

55361

Research Area

Signal Transduction, Metabolism