anti- PHOX2B antibody

Host

Mouse

Uniprot ID

Q99453

Form

liquid

Purification

Protein A+G purification

Purity

? 95% as determined by SDS-PAGE

Clonality

monoclonal

Clone ID

2B0

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.

Immunogen

paired-like homeobox 2b

Synonyms

NBPhox, Neuroblastoma Phox, paired like homeobox 2b, PHOX2B, PHOX2B homeodomain protein, PMX2B

Observed MW

35 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, IHC, WB

Recommended dilution

WB: 1:1000-1:5000; IHC: 1:20-1:200

Gene ID

8929

Research Area

Neuroscience, Epigenetics, Metabolism, Developmental biology