anti- PHOX2B antibody

Host

Rabbit

Uniprot ID

Q99453

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.

Immunogen

paired-like homeobox 2b

Synonyms

PMX2B

Observed MW

31 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IF, IHC

Recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID

8929

Research Area

Neuroscience, Epigenetics, Metabolism, Developmental biology