anti- PFKFB3-Specific antibody

Host

Rabbit

Uniprot ID

Q16875

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

PFKFB3, also named as NY-REN-56 and iPFK-2, plays a role in glucose metabolism. It synthesis and degradation of fructose 2,6-bisphosphate. Endogenously generated adenosine cooperates with bacterial components to increase PFKFB3 isozyme activity, resulting in greater fructose 2,6-bisphosphate accumulation. PFKFB3 is required for increased growth, metabolic activity and is regulated through active JAK2 and STAT5. This antibody is specific to PFKFB3.

Immunogen

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

Synonyms

6PF 2 K/Fru 2,6 P2ase 3, FLJ37326, IPFK2, PFK/FBPase 3, PFK2, PFKFB3

Observed MW

58 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IF

Recommended dilution

WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200

Gene ID

5209

Research Area

Metabolism