anti- PER2 antibody

Host

Rabbit

Uniprot ID

O15055

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

PER2, also named as KIAA0347, is a component of the circadian clock mechanism which is essential for generating circadian rhythms. PER2 is a negative element in the circadian transcriptional loop. PER2 influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. It negatively regulates CLOCK|NPAS2-BMAL1|BMAL2-induced transactivation. Defects in PER2 are a cause of familial advanced sleep-phase syndrome (FASPS) which is characterized by very early sleep onset and offset.

Immunogen

period homolog 2

Synonyms

FASPS, hPER2, KIAA0347, PER2, period homolog 2

Observed MW

136 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IP

Recommended dilution

WB: 1:500-1:2000; IP: 1:200-1:1000

Gene ID

5697

Research Area

Neuroscience, Cardiovascular, Metabolism, Signal Transduction