anti- PDS5B antibody

Host

Rabbit

Uniprot ID

Q9NTI5

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.

Immunogen

PDS5, regulator of cohesion maintenance, homolog B(S. cerevisiae)

Synonyms

APRIN, AS3,

Observed MW

165-170KD

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB

Recommended dilution

WB: 1:500-1:2000

Gene ID

23047

Research Area

Cell Division and Proliferation, Developmental biology