anti- PDE5A antibody

Host

Rabbit

Uniprot ID

O76074

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP(PubMed:9714779, PubMed:15489334). Specifically regulates nitric-oxide-generated cGMP(PubMed:15489334).

Immunogen

phosphodiesterase 5A, cGMP-specific

Synonyms

PDE5

Observed MW

100KD

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IF

Recommended dilution

WB: 1:500-1:2000; IF: 1:20-1:200

Gene ID

8654

Research Area

Cardiovascular, Metabolism, Developmental biology, Signal Transduction