anti- PDE3B antibody

Host

Rabbit

Uniprot ID

Q13370

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

Immunogen

phosphodiesterase 3B, cGMP-inhibited

Synonyms

CGI PDE B, CGIP1, cGIPDE1, HcGIP1, PDE3B

Observed MW

124 kDa

Reactivity

Human

Tested Application

ELISA, IP

Recommended dilution

IP: 1:200-1:2000

Gene ID

5140

Research Area

Signal Transduction, Metabolism