anti- PAPD5 antibody

Host

Rabbit

Uniprot ID

Q8NDF8

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity(in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.

Immunogen

PAP associated domain containing 5

Synonyms

PAPD5, Terminal uridylyltransferase 3, TRF4 2, TUTase 3

Observed MW

50 kDa, 80 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IP

Recommended dilution

WB: 1:500 - 1:2000

Gene ID

64282

Research Area

Metabolism