anti- P62/SQSTM1 antibody

Host

Rabbit

Uniprot ID

Q13501

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Immunogen

sequestosome 1

Synonyms

P62, sequestosome 1, SQSTM1, Ubiquitin binding protein p62

Observed MW

62 kDa

Reactivity

Human

Tested Application

ELISA, WB, IHC, IF, IP

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; IP: 1:20 - 1:50

Gene ID

8878

Research Area

Neuroscience, Cardiovascular, Metabolism, Signal Transduction