anti- p120 Catenin antibody

Host

Rabbit

Uniprot ID

O60716

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway(By similarity). Associates with and regulates the cell adhesion properties of both C-, E-and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.

Immunogen

catenin, delta 1

Synonyms

CAS, Catenin delta 1, CTNND, CTNND1, KIAA0384, p120, p120 Catenin, p120(cas), p120(ctn), P120CAS, p120-catenin, P120CTN

Observed MW

105kd,66kd

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IF, IP,IHC

Recommended dilution

WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:10-1:100

Gene ID

Research Area

Cancer, Immunology, Signal Transduction, Metabolism