anti- P-selectin antibody

Host

Rabbit

Uniprot ID

P16109

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.

Immunogen

selectin P(granule membrane protein 140kDa, antigen CD62)

Synonyms

CD62, CD62P, FLJ45155, GMP 140, GMP140, GMRP, Granule membrane protein 140, GRMP, LECAM3, PADGEM, PSEL, P-selectin, SELP

Observed MW

91 kDa

Reactivity

Human

Tested Application

ELISA, IHC

Recommended dilution

IHC: 1:20-1:200

Gene ID

Research Area

Immunology, Cardiovascular, Signal Transduction