anti- Osteopontin antibody

Host

Rabbit

Uniprot ID

P10451

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Osteopontin(OPN), also known as SPP1, is a secreted glycophosphoprotein that belongs to the small integrin-binding ligand N-linked glycoprotein(SIBLING) family. Originally isolated from bone, OPN has been found in kidney, vascular tissues, biological fluids, and various tumor tissues(PMID: 15138464; 16406521). OPN can interact with CD44 and integrins and regulate diverse biological processes. It has a multifaceted role in bone development and remodeling, and is also involved in the inflammatory and immune response, oncogenesis and cancer progression.

Immunogen

secreted phosphoprotein 1

Synonyms

BNSP, Bone sialoprotein 1, BSPI, ETA 1, Nephropontin, OPN, Osteopontin, secreted phosphoprotein 1, SPP 1, SPP1, Urinary stone protein, Uropontin

Observed MW

66 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, IHC, WB, IF

Recommended dilution

WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200

Gene ID

6696

Research Area

Neuroscience, Stem Cells, Immunology, Cardiovascular