anti- OFD1 antibody

Host

Rabbit

Uniprot ID

O75665

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. The cilium is a cell surface projection found in many vertebrate cells required to transduce signals important for development and tissue homeostasis. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis. Only OFD1 localized at the centriolar satellites is removed by autophagy, which is an important step in the ciliogenesis regulation(By similarity).

Immunogen

oral-facial-digital syndrome 1

Synonyms

CXorf5

Observed MW

43 kDa

Reactivity

Human

Tested Application

ELISA, IHC, WB

Recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Gene ID

8481

Research Area

stem cells