anti- NXF1 antibody

Host

Rabbit

Uniprot ID

Q9UBU9

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements(CTE) and in the export of mRNA from the nucleus to the cytoplasm(TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export.

Immunogen

nuclear RNA export factor 1

Synonyms

MEX67, mRNA export factor TAP, nuclear RNA export factor 1, NXF1, TAP, Tip associated protein, Tip associating protein

Observed MW

66-70 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IF

Recommended dilution

WB : 1:500-1:1000; IF : 1:20-1:200

Gene ID

10482

Research Area

Metabolism