anti- NR3C2 antibody

Host

Rabbit

Uniprot ID

P08235

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Receptor for both mineralocorticoids(MC) such as aldosterone and glucocorticoids(GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements(MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.

Immunogen

nuclear receptor subfamily 3, group C, member 2

Synonyms

MCR, Mineralocorticoid receptor, MLR, MR, NR3C2

Observed MW

107 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IF, IP

Recommended dilution

WB: 1:500-1:2000; IP: 1:500-1:1000 ; IHC: 1:20-1:200; IF: 1:10-1:100

Gene ID

4306

Research Area

Cardiovascular, Metabolism, Signal Transduction