anti- NR2E3 antibody

Host

Rabbit

Uniprot ID

Q9Y5X4

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod-and cone-specific genes, including rhodopsin, M-and S-opsin and rod-specific phosphodiesterase beta subunit. Enhances rhodopsin expression. Represses M-and S-cone opsin expression.

Immunogen

nuclear receptor subfamily 2, group E, member 3

Synonyms

ESCS, NR2E3, PNR, rd7, RNR, RP37

Observed MW

43-45 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IF, FC

Recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:100

Gene ID

10002

Research Area

Signal Transduction, Metabolism, Developmental biology, Neuroscience, Stem Cells