anti- NKIRAS2 antibody

Host

Rabbit

Uniprot ID

Q9NYR9

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta(NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP-and GDP-bound forms block phosphorylation of NFKBIB(By similarity).

Immunogen

NFKB inhibitor interacting Ras-like 2

Synonyms

KBRAS2

Observed MW

22 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IF

Recommended dilution

WB: 1:500-1:2000; IF: 1:20-1:200

Gene ID

28511

Research Area

Signal Transduction