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ABCbiolab

SKU:ABCF05591

anti- NFX1 antibody

anti- NFX1 antibody

Regular price $260.00 USD
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size
Host
Uniprot ID

Host

Rabbit

Uniprot ID

Q12986

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

as determined by SDS-PAGE

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination.

Immunogen

nuclear transcription factor, X-box binding 1

Synonyms

NFX2

Observed MW

124kd

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB

Recommended dilution

WB: 1:500-1:2000

Gene ID

4799

Research Area

Metabolism

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