anti- NET1 antibody

Host

Rabbit

Uniprot ID

Q7Z628

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Acts as guanine nucleotide exchange factor(GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.

Immunogen

neuroepithelial cell transforming 1

Synonyms

ARHGEF8

Observed MW

62-68 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IF, IHC

Recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID

10276

Research Area

Signal Transduction, Metabolism, Cancer, Immunology