anti- NELFB antibody

Host

Rabbit

Uniprot ID

Q8WX92

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding.

Immunogen

cofactor of BRCA1

Synonyms

COBRA1, KIAA1182

Observed MW

66 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IP, IF

Recommended dilution

WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100

Gene ID

25920

Research Area

Metabolism