anti- NCOA3 antibody

Host

Rabbit

Uniprot ID

Q9Y6Q9

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids(GR and ER), retinoids(RARs and RXRs), thyroid hormone(TRs), vitamin D3(VDR) and prostanoids(PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.

Immunogen

nuclear receptor coactivator 3

Synonyms

AIB1, BHLHE42, RAC3, TRAM1

Observed MW

160kd

Reactivity

Human

Tested Application

ELISA, WB, IF, IHC, FC

Recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID

8202

Research Area

Metabolism