anti- NCKIPSD antibody

Host

Rabbit

Uniprot ID

Q9NZQ3

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Has an important role in stress fiber formation induced by active diaphanous protein homolog 1(DRF1). Induces microspike formation, in vivo(By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42(By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis.

Immunogen

NCK interacting protein with SH3 domain

Synonyms

AF3P21, SPIN90

Observed MW

80 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC, IP

Recommended dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

Gene ID

51517

Research Area

Signal Transduction