anti- NANOS3 antibody

Host

Rabbit

Uniprot ID

P60323

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and-independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells(PGCs) from apoptosis.

Immunogen

nanos homolog 3(Drosophila)

Synonyms

Nanos homolog 3, nanos homolog 3 (Drosophila), NANOS1L, NANOS3, NOS 3, NOS3

Observed MW

26-30 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:200-1:1000; IHC: 1:50-1:500

Gene ID

342977

Research Area

Cell Division and Proliferation, Developmental biology