anti- CDC25B antibody

Host

Rabbit

Uniprot ID

P30305

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

CDC25B, also named as CDC25HU2, belongs to the MPI phosphatase family. It is a tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. CDC25B directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity. In Jurkat cell, this antibody recognized 2 bands: 60kd(isoform 2, CDC25B2) and 70kd(isoform 4 of CDC25B).

Immunogen

cell division cycle 25 homolog B(S. pombe)

Synonyms

CDC25B, CDC25HU2, M phase inducer phosphatase 2

Observed MW

60-70 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IHC, IP

Recommended dilution

WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200

Gene ID

994

Research Area

Cancer, Cell Division and Proliferation, Metabolism