anti- CD68 antibody

Host

Mouse

Uniprot ID

P34810

Form

liquid

Purification

Protein A+G purification

Purity

? 95% as determined by SDS-PAGE

Clonality

monoclonal

Clone ID

0F8

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue-and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

Immunogen

CD68 molecule

Synonyms

CD68, CD68 molecule, GP110, Macrosialin, SCARD1

Observed MW

Reactivity

Human

Tested Application

ELISA, IHC

Recommended dilution

IHC: 1:500-1:2000

Gene ID

968

Research Area

Neuroscience, Stem Cells, Immunology, Cancer