anti- Cd2ap antibody

Host

Rabbit

Uniprot ID

Q9Y5K6

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.

Immunogen

CD2-associated protein

Synonyms

Observed MW

70 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IF, IP

Recommended dilution

WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100

Gene ID

23607

Research Area

Signal Transduction