anti- CD20 antibody

Host

Rabbit

Uniprot ID

P11836

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

CD20 is a 33-37 kDa transmembrane phosphoprotein. CD20 is a B-lymphocyte surface molecule that is widely expressed during B-cell ontogeny, from early pre-B-cell developmental stages until final differentiation into plasma cells. CD20 functions as calcium-permeable cation channel. It is involved in the regulation of B-cell activation and proliferation. CD20 serves as a useful target for antibody-mediated therapeutic depletion of B-cells.

Immunogen

membrane-spanning 4-domains, subfamily A, member 1

Synonyms

B lymphocyte antigen CD20, B1, Bp35, CD20, LEU 16, MS4A1, MS4A2, S7

Observed MW

33 kDa

Reactivity

Human

Tested Application

ELISA, WB, IHC, FC

Recommended dilution

WB: 1:1000-1:8000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:50-1:500

Gene ID

Research Area

Stem Cells, Immunology, Signal Transduction, Cancer