anti- CD11c/Integrin alpha X antibody

Host

Mouse

Uniprot ID

P20702

Form

liquid

Purification

Protein A+G purification

Purity

? 95% as determined by SDS-PAGE

Clonality

monoclonal

Clone ID

5D4

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. CD11c/Integrin alpha X is a type I transmembrane protein present on a variety of cells, including monocytes/macrophages, granulocytes, NK cells and dendritic cells. Integrin alpha X/beta 2 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis.

Immunogen

integrin, alpha X(complement component 3 receptor 4 subunit)

Synonyms

CD11C, Integrin alpha X, ITGAX, Leu M5, SLEB6

Observed MW

150 kDa

Reactivity

Human, Mouse

Tested Application

ELISA, WB, IHC

Recommended dilution

WB: 1:500-1:5000; IHC: 1:100-1:400

Gene ID

Research Area

Cancer, Immunology