anti- CCNY antibody

Host

Rabbit

Uniprot ID

Q8ND76

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.

Immunogen

cyclin Y

Synonyms

C10orf9, CBCP1, CFP1

Observed MW

33-39 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IF, IP

Recommended dilution

WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100

Gene ID

219771

Research Area

Stem Cells