anti- Caspase 9 antibody

Host

Rabbit

Uniprot ID

P55211

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Caspase 9, apoptosis-related cysteine protease(CASP9, synonyms: MCH6, APAF3, APAF-3, ICE-LAP6, CASPASE-9c)is a member of the cysteine-aspartic acid protease(caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. Caspase 9 is processed by APAF1; this step is thought to be one of the earliest in the caspase activation cascade. FNab01295 can recognize the pre-and cleaved-caspase 9.

Immunogen

caspase 9, apoptosis-related cysteine peptidase

Synonyms

APAF 3, APAF3, Apoptotic protease Mch 6, CASP 9, CASP9, Caspase 9, CASPASE 9c, Caspase9, Caspase-9, ICE LAP6, ICE like apoptotic protease 6, MCH6

Observed MW

46kd

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, IF, IHC, IP, WB, FC

Recommended dilution

WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:200; IF: 1:10-1:100

Gene ID

842

Research Area

Metabolism