anti- CARD11 antibody

Host

Rabbit

Uniprot ID

Q9BXL7

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

Involved in the costimulatory signal essential for T-cell receptor(TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10.

Immunogen

caspase recruitment domain family, member 11

Synonyms

CARMA1

Observed MW

133 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IF, IHC

Recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID

84433

Research Area

Immunology, Signal Transduction