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ABCbiolab

SKU:ABCF00958

anti- BUB1 antibody

anti- BUB1 antibody

Regular price $240.00 USD
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size
Host
Uniprot ID

Host

Rabbit

Uniprot ID

O43683

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

as determined by SDS-PAGE

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background

This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.

Immunogen

budding uninhibited by benzimidazoles 1 homolog (yeast)

Synonyms

BUB1L

Observed MW

133 kDa

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, IHC, WB

Recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Gene ID

699

Research Area

Cancer, Cell Division and Proliferation, Metabolism, Developmental biology

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