SKU:ABCF00958
anti- BUB1 antibody
anti- BUB1 antibody
Host
Rabbit
Uniprot ID
O43683
Form
liquid
Purification
Immunogen affinity purified
Purity
>= 95%
as determined by SDS-PAGEClonality
polyclonal
Clone ID
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.
Immunogen
budding uninhibited by benzimidazoles 1 homolog (yeast)
Synonyms
BUB1L
Observed MW
133 kDa
Reactivity
Human, Mouse, Rat
Tested Application
ELISA, IHC, WB
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Gene ID
699
Research Area
Cancer, Cell Division and Proliferation, Metabolism, Developmental biology