anti- BMPR2 antibody

Host

Rabbit

Uniprot ID

Q13873

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.

Immunogen

bone morphogenetic protein receptor, type II(serine/threonine kinase)

Synonyms

PPH1

Observed MW

120kd,97kd

Reactivity

Human, Mouse, Rat

Tested Application

ELISA, WB, IP

Recommended dilution

WB: 1:500-1:2000; IP: 1:500-1:1000

Gene ID

659

Research Area

Signal Transduction, Metabolism, Cardiovascular, Developmental biology, Stem Cells