SKU:ABCF00890
anti- BMP2 antibody
anti- BMP2 antibody
Host
Rabbit
Uniprot ID
P12643
Form
liquid
Purification
Immunogen affinity purified
Purity
>= 95%
as determined by SDS-PAGEClonality
polyclonal
Clone ID
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
Immunogen
bone morphogenetic protein 2
Synonyms
BMP2A
Observed MW
45 kDa
Reactivity
Human, Mouse, Rat
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Gene ID
650
Research Area
Stem Cells, Developmental biology