anti- BDNF antibody

Host

Rabbit

Uniprot ID

P23560

Form

liquid

Purification

Immunogen affinity purified

Purity

>= 95%

Clonality

polyclonal

Clone ID

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

Background

During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation(LTP), long-term depression(LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

Immunogen

brain-derived neurotrophic factor

Synonyms

BDNF, ANON2, BULN2, brain-derived neurotrophic factor

Observed MW

28-37 kDa, 14 kDa

Reactivity

Human, Rat, Mouse

Tested Application

ELISA, WB, IHC,IF

Recommended dilution

WB: 1:200-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500

Gene ID

627

Research Area

Neuroscience, Signal Transduction, Developmental biology